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Flunitrazepam Powder (Rohypnol) is a central nervous system depressant. It is similar to diazepam (such as Valium) but about 10 times more potent. It is commonly called roofies. It is a tasteless, odorless tablet that can be crushed and dissolved in liquid. It has been used in date rapes, because it can be slipped into a person’s drink without it being detected. One small tablet can produce effects for 8 to 12 hours.

What is Flunitrazepam Powder?

Flunitrazepam has a long half-life of 18–26 hours, which means that flunitrazepam’s effects after nighttime administration persist throughout the next day. This is due to the production of active metabolites. These metabolites further increase the duration of drug action compared to benzodiazepines that produce nonactive metabolites.

What are the risks?

Flunitrazepam Powder is lipophilic and is metabolised by the liver via oxidative pathways. The enzyme CYP3A4 is the main enzyme in its phase 1 metabolism in human liver microsomes. While 80% of flunitrazepam that is taken orally is absorbed, bioavailability in suppository form is closer to 50%.

 Is Rohypnol illegal in my Country?

Flunitrazepam has also been administered as a concurrent dose for patients that are taking ketamine. Rohypnol lowers the side effects of the anesthetic (ketamine), resulting in less confusion in awakening states, less negative influence on pulse rate, and fewer fluctuations in blood pressure.

How long does Flunitrazepam last in the body?

Flunitrazepam, as with other benzodiazepines, can lead to drug dependence. Discontinuation may result in benzodiazepine withdrawal syndrome, characterised by seizures, psychosis, insomnia, and anxiety. Rebound insomnia, worse than baseline insomnia, typically occurs after discontinuation of flunitrazepam even from short-term single nightly dose therapy.

What are the effects of Rohypnol Powder?

Flunitrazepam has been advised to be prescribed only for short-term use or by those with chronic insomnia on an occasional basis. In countries where this drug is used, it is used for treatment of severe cases of sleep disorders, and in some countries as a preanesthetic agent. These were also the uses for which it was originally studied.

Who Should take Flunitrazepam?