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Alprazolam is mostly used in short-term management of anxiety disorders, panic disorders, and nausea due to chemotherapy. Alprazolam is indicated for the treatment of generalized anxiety disorder and panic disorder with or without agoraphobia in adults. The FDA label advises that the physician should periodically reassess the usefulness of the drug. Alprazolamum is generally taken by mouth.

What is Alprazolam?

Alprazolam, sold under the brand name Xanax, among others, is a fast-acting, potent tranquilizer of medium duration in the triazolobenzodiazepine (TBZD) class, which are benzodiazepines (BZDs) fused with a triazole ring. It is most commonly used in short-term management of anxiety disorders, specifically panic disorder or generalized anxiety disorder (GAD).

Who should use Alprazolam?

Common side effects include sleepiness, depression, headaches, feeling tired, dry mouth, and memory problems. Some of the sedation and tiredness may improve within a few days. Due to concerns about misuse, some do not recommend alprazolamum as an initial treatment for panic disorder.[1] Other uses include the treatment of chemotherapy-induced nausea, together with other treatments. GAD improvement occurs generally within a week.

Effects of Triazolobenzodiazepine

Alprazolam is effective in the relief of moderate to severe anxiety and panic attacks. However, it is not a first-line treatment since the development of selective serotonin reuptake inhibitors. Alprazolam is not recommended in Australia for the treatment of panic disorder because of concerns regarding tolerance, dependence, and abuse.[2]

Which are the Strongest Benzodiazepines

Alprazolam is a positive allosteric modulator of the gamma-aminobutyric acid (GABA) type A receptor. When it binds to the receptor, effects of GABA are enhanced leading to inhibition of neurons in the brain. This results in effects including reduced anxiety, muscle relaxant, antidepressant and anticonvulsant activity. The activity of Alprazolamum in the central nervous system is dose dependent.

How long does Alprazolamum last in the body?

As a benzodiazepine, alprazolam produces a variety of therapeutic and adverse effects by binding to the GABA_A benzodiazepine receptor site and modulating its function; GABA receptors are the most prolific inhibitory receptor within the brain.

8-Chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine