A normal average dose of 2,5-Dimethoxy-4-chloroamphetamine ranges from 0.5–7.0 mg the former producing threshold effects, and the latter producing extremely strong effects. Onset of the drug is 1–3 hours, peak and plateau at 4–8 hours, and a gradual come down with residual stimulation at 9-20h. After effects can last well into the next day.
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Unlike simple amphetamines, 2,5-Dimethoxy-4-chloroamphetamine is considered a chemical that influences cognitive and perception processes of the brain. The strongest supposed effects include open and closed eye visuals, increased awareness of sound and movement, and euphoria. In the autobiography PiHKAL, Alexander Shulgin included a description of DOC as “an archetypalpsychedelic” (#64); its presumed full-range visual, audio, physical, and mental effects show exhilarating clarity, and some overwhelming, humbling, and “composting”/interweaving effects.
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DOC may be quantitated in blood, plasma or urine by gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry to confirm a diagnosis of poisoning in hospitalized patients or to provide evidence in a medicolegal death investigation. Blood or plasma 2,5-Dimethoxy-4-chloroamphetamine concentrations are expected to be in a range of 1–10 μg/L in persons using the drug recreationally, >20 μg/L in intoxicated patients and >100 μg/L in victims of acute overdose.
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Other Names; 1-(4-Chloro-2,5-dimethoxy-phenyl)propan-2-amine; DOC Powder; 4-Chloro-2,5-dimethoxyamphetamine; 3C-C, 4-Cl-2,5-DMA, 4-Chloro-2,5-DMA; 4-Chloro-2,5-dimethoxyamfetamine, 4-Chloro-2,5-dimethoxyphenylisopropylamine, CAS 123431-31-2